Kết quả phiên chạy FP3 của chặng đua GP Mỹ 2021:
| Stt | Tay đua | Xe | Thời gian | Kh/cách | Lap |
| 1 | Sergio Perez | RED BULL | 1:34.701 | 13 | |
| 2 | Carlos Sainz | FERRARI | 1:34.805 | +0.104s | 16 |
| 3 | Max Verstappen | RED BULL | 1:34.912 | +0.211s | 13 |
| 4 | Lando Norris | MCLAREN | 1:34.945 | +0.244s | 13 |
| 5 | Valtteri Bottas | MERCEDES | 1:34.988 | +0.287s | 15 |
| 6 | Lewis Hamilton | MERCEDES | 1:35.219 | +0.518s | 16 |
| 7 | Daniel Ricciardo | MCLAREN | 1:35.345 | +0.644s | 11 |
| 8 | Pierre Gasly | ALPHATAURI | 1:35.398 | +0.697s | 17 |
| 9 | Charles Leclerc | FERRARI | 1:35.688 | +0.987s | 17 |
| 10 | Esteban Ocon | ALPINE | 1:35.711 | +1.010s | 10 |
| 11 | Sebastian Vettel | ASTON MARTIN | 1:35.851 | +1.150s | 18 |
| 12 | George Russell | WILLIAMS | 1:36.023 | +1.322s | 9 |
| 13 | Kimi Räikkönen | ALFA ROMEO | 1:36.062 | +1.361s | 20 |
| 14 | Nicholas Latifi | WILLIAMS | 1:36.118 | +1.417s | 8 |
| 15 | Antonio Giovinazzi | ALFA ROMEO | 1:36.252 | +1.551s | 16 |
| 16 | Lance Stroll | ASTON MARTIN | 1:36.392 | +1.691s | 13 |
| 17 | Fernando Alonso | ALPINE | 1:36.490 | +1.789s | 12 |
| 18 | Yuki Tsunoda | ALPHATAURI | 1:36.572 | +1.871s | 16 |
| 19 | Mick Schumacher | HAAS | 1:36.671 | +1.970s | 15 |
| 20 | Nikita Mazepin | HAAS | 2:03.456 | +28.755s | 15 |
Nguồn: Tổng hợp
