Kết quả phiên chạy FP4 của chặng đua MotoGP Emilia Romagna 2021:
| Stt | Tay đua | Xe | Km/h | Thời gian | Kh/cách |
| 1 | Iker LECUONA | KTM | 291.8 | 1’37.441 | |
| 2 | Francesco BAGNAIA | Ducati | 298.3 | 1’37.535 | 0.094 / 0.094 |
| 3 | Jack MILLER | Ducati | 297.5 | 1’38.848 | 1.407 / 1.313 |
| 4 | Fabio QUARTARARO | Yamaha | 291.8 | 1’38.889 | 1.448 / 0.041 |
| 5 | Miguel OLIVEIRA | KTM | 292.6 | 1’39.149 | 1.708 / 0.260 |
| 6 | Maverick VIÑALES | Aprilia | 295.0 | 1’40.018 | 2.577 / 0.869 |
| 7 | Luca MARINI | Ducati | 294.2 | 1’40.177 | 2.736 / 0.159 |
| 8 | Danilo PETRUCCI | KTM | 288.7 | 1’40.311 | 2.870 / 0.134 |
| 9 | Johann ZARCO | Ducati | 294.2 | 1’41.238 | 3.797 / 0.927 |
| 10 | Alex RINS | Suzuki | 294.2 | 1’41.269 | 3.828 / 0.031 |
| 11 | Franco MORBIDELLI | Yamaha | 285.7 | 1’41.306 | 3.865 / 0.037 |
| 12 | Jorge MARTIN | Ducati | 294.2 | 1’41.430 | 3.989 / 0.124 |
| 13 | Valentino ROSSI | Yamaha | 286.4 | 1’41.893 | 4.452 / 0.463 |
| 14 | Takaaki NAKAGAMI | Honda | 294.2 | 1’42.279 | 4.838 / 0.386 |
| 15 | Brad BINDER | KTM | 291.8 | 1’42.562 | 5.121 / 0.283 |
| 16 | Andrea DOVIZIOSO | Yamaha | 283.4 | 1’42.794 | 5.353 / 0.232 |
| 17 | Michele PIRRO | Ducati | 274.1 | 1’43.069 | 5.628 / 0.275 |
| 18 | Pol ESPARGARO | Honda | 295.0 | 1’43.465 | 6.024 / 0.396 |
| 19 | Marc MARQUEZ | Honda | 284.2 | 1’43.585 | 6.144 / 0.120 |
| Joan MIR | Suzuki | 283.4 | 1’44.337 | 6.896 / 0.752 | |
| Alex MARQUEZ | Honda | 288.7 | 1’44.345 | 6.904 / 0.008 | |
| Aleix ESPARGARO | Aprilia | 279.7 | 1’44.974 | 7.533 / 0.629 | |
| Enea BASTIANINI | Ducati | 287.2 | 1’47.606 | 10.165 / 2.632 | |
| Lorenzo SAVADORI | Aprilia |
Nguồn: Tổng hợp
