Kết quả phiên chạy FP1 của chặng đua MotoGP San Marino 2021:
| Stt | Tay đua | Xe | Km/h | Thời gian | Kh/cách |
| 1 | Maverick VIÑALES | Aprilia | 295.8 | 1’32.666 | |
| 2 | Joan MIR | Suzuki | 291.8 | 1’32.746 | 0.080 / 0.080 |
| 3 | Francesco BAGNAIA | Ducati | 294.2 | 1’32.801 | 0.135 / 0.055 |
| 4 | Jack MILLER | Ducati | 296.7 | 1’32.859 | 0.193 / 0.058 |
| 5 | Alex RINS | Suzuki | 295.0 | 1’32.885 | 0.219 / 0.026 |
| 6 | Pol ESPARGARO | Honda | 297.5 | 1’33.019 | 0.353 / 0.134 |
| 7 | Fabio QUARTARARO | Yamaha | 288.7 | 1’33.024 | 0.358 / 0.005 |
| 8 | Stefan BRADL | Honda | 295.8 | 1’33.047 | 0.381 / 0.023 |
| 9 | Marc MARQUEZ | Honda | 295.0 | 1’33.100 | 0.434 / 0.053 |
| 10 | Aleix ESPARGARO | Aprilia | 294.2 | 1’33.102 | 0.436 / 0.002 |
| 11 | Johann ZARCO | Ducati | 298.3 | 1’33.143 | 0.477 / 0.041 |
| 12 | Enea BASTIANINI | Ducati | 296.7 | 1’33.314 | 0.648 / 0.171 |
| 13 | Takaaki NAKAGAMI | Honda | 296.7 | 1’33.409 | 0.743 / 0.095 |
| 14 | Jorge MARTIN | Ducati | 295.0 | 1’33.451 | 0.785 / 0.042 |
| 15 | Michele PIRRO | Ducati | 293.4 | 1’33.482 | 0.816 / 0.031 |
| 16 | Franco MORBIDELLI | Yamaha | 286.4 | 1’33.570 | 0.904 / 0.088 |
| 17 | Iker LECUONA | KTM | 290.3 | 1’33.710 | 1.044 / 0.140 |
| 18 | Alex MARQUEZ | Honda | 295.8 | 1’33.766 | 1.100 / 0.056 |
| 19 | Valentino ROSSI | Yamaha | 289.5 | 1’33.791 | 1.125 / 0.025 |
| 20 | Danilo PETRUCCI | KTM | 288.7 | 1’33.950 | 1.284 / 0.159 |
| 21 | Brad BINDER | KTM | 293.4 | 1’34.022 | 1.356 / 0.072 |
| 22 | Miguel OLIVEIRA | KTM | 294.2 | 1’34.026 | 1.360 / 0.004 |
| 23 | Luca MARINI | Ducati | 292.6 | 1’34.037 | 1.371 / 0.011 |
| 24 | Andrea DOVIZIOSO | Yamaha | 288.0 | 1’35.211 | 2.545 / 1.174 |
Nguồn: Tổng hợp
