Bảng xếp hạng tay đua MotoGP 2021 (sau chặng 15-Americas):
| Stt | Tay đua | Xe | Điểm |
| 1 | Fabio QUARTARARO | Yamaha | 254 |
| 2 | Francesco BAGNAIA | Ducati | 202 |
| 3 | Joan MIR | Suzuki | 175 |
| 4 | Jack MILLER | Ducati | 149 |
| 5 | Johann ZARCO | Ducati | 141 |
| 6 | Brad BINDER | KTM | 131 |
| 7 | Marc MARQUEZ | Honda | 117 |
| 8 | Aleix ESPARGARO | Aprilia | 104 |
| 9 | Maverick VIÑALES | Aprilia | 98 |
| 10 | Miguel OLIVEIRA | KTM | 92 |
| 11 | Jorge MARTIN | Ducati | 82 |
| 12 | Alex RINS | Suzuki | 81 |
| 13 | Enea BASTIANINI | Ducati | 71 |
| 14 | Takaaki NAKAGAMI | Honda | 70 |
| 15 | Pol ESPARGARO | Honda | 70 |
| 16 | Alex MARQUEZ | Honda | 54 |
| 17 | Franco MORBIDELLI | Yamaha | 40 |
| 18 | Iker LECUONA | KTM | 38 |
| 19 | Danilo PETRUCCI | KTM | 37 |
| 20 | Luca MARINI | Ducati | 30 |
| 21 | Valentino ROSSI | Yamaha | 29 |
| 22 | Stefan BRADL | Honda | 13 |
| 23 | Michele PIRRO | Ducati | 8 |
| 24 | Dani PEDROSA | KTM | 6 |
| 25 | Lorenzo SAVADORI | Aprilia | 4 |
| 26 | Andrea DOVIZIOSO | Yamaha | 3 |
| 27 | Tito RABAT | Ducati | 1 |
| 28 | Cal CRUTCHLOW | Yamaha | |
| 29 | Garrett GERLOFF | Yamaha | |
| 30 | Jake DIXON | Yamaha |
Nguồn: MotoGP
