Kết quả phiên chạy FP1 của GP Mỹ 2021:
| Stt | Tay đua | Xe | Thời gian | Kh/cách | LAP |
| 1 | Valtteri Bottas | MERCEDES | 1:34.874 | 17 | |
| 2 | Lewis Hamilton | MERCEDES | 1:34.919 | +0.045s | 18 |
| 3 | Max Verstappen | RED BULL | 1:35.806 | +0.932s | 16 |
| 4 | Charles Leclerc | FERRARI | 1:36.334 | +1.460s | 18 |
| 5 | Carlos Sainz | FERRARI | 1:36.508 | +1.634s | 20 |
| 6 | Pierre Gasly | ALPHATAURI | 1:36.611 | +1.737s | 18 |
| 7 | Sergio Perez | RED BULL | 1:36.798 | +1.924s | 20 |
| 8 | Lando Norris | MCLAREN | 1:36.855 | +1.981s | 11 |
| 9 | Antonio Giovinazzi | ALFA ROMEO | 1:36.874 | +2.000s | 18 |
| 10 | Kimi Räikkönen | ALFA ROMEO | 1:36.876 | +2.002s | 18 |
| 11 | George Russell | WILLIAMS | 1:36.966 | +2.092s | 19 |
| 12 | Esteban Ocon | ALPINE | 1:36.970 | +2.096s | 22 |
| 13 | Lance Stroll | ASTON MARTIN | 1:36.972 | +2.098s | 20 |
| 14 | Sebastian Vettel | ASTON MARTIN | 1:36.982 | +2.108s | 20 |
| 15 | Fernando Alonso | ALPINE | 1:37.068 | +2.194s | 12 |
| 16 | Daniel Ricciardo | MCLAREN | 1:37.458 | +2.584s | 18 |
| 17 | Nicholas Latifi | WILLIAMS | 1:37.463 | +2.589s | 19 |
| 18 | Yuki Tsunoda | ALPHATAURI | 1:37.954 | +3.080s | 22 |
| 19 | Mick Schumacher | HAAS | 1:38.866 | +3.992s | 17 |
| 20 | Nikita Mazepin | HAAS | 1:42.239 | +7.365s | 19 |
Nguồn: Tổng hợp
